This is a neuroimaging study conducted at McLean Hospital which is focused on studying changes in functional brain network architecture in patients with OCD over the course of intensive, residential treatment.
The goal of this project is to study changes in brain networks and harm avoidance behavior that track with OCD-related symptoms and illness behavior over the course of 8-week residential treatment, using a longitudinal, repeated measures design complemented by intensive longitudinal assessment.
While substantial prior research has provided valuable insights into the underlying neurobiology of OCD, most studies of neuropsychiatric signs and symptoms have focused on either clinician-report or self-report measures, or have employed neuropsychological tests or cognitive neuroscience tasks, as the behavioral readout with which to correlate biological findings. We aim to use technology to target individual patients by revealing behavioral abnormalities using actigraphy signals.
