Intensive Real-Time Computational Phenotyping in Individuals with Borderline Personality Disorder

The scientific motivation for longitudinal study of individuals with mental illness has increasingly become an imperative, if we are to translate biological insights into discoveries that benefit individual patients. For studies intended to reveal differences between patients and healthy individuals at a group level, characterizing patients during periods of profound changes in mental status is a sensible approach, since it maximizes biological signal while minimizing the need to keep track of patients over time.